Note
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During a dMRI acquisition, the subject motion inevitable. This motion implies a misalignment between N volumes on a dMRI dataset. A common way to solve this issue is to perform a registration on each acquired volume to a reference b = 0. [JenkinsonSmith01]
This preprocessing is an highly recommended step that should be executed before any dMRI dataset analysis.
Let’s import some essential functions.
from dipy.align import motion_correction
from dipy.core.gradients import gradient_table
from dipy.data import get_fnames
from dipy.io.image import load_nifti, save_nifti
from dipy.io.gradients import read_bvals_bvecs
We choose one of the data from the datasets in dipy_. However, you can replace the following line with the path of your image.
dwi_fname, dwi_bval_fname, dwi_bvec_fname = get_fnames('sherbrooke_3shell')
We load the image and the affine of the image. The affine is the transformation matrix which maps image coordinates to world (mm) coordinates. We also load the b-values and b-vectors.
data, affine = load_nifti(dwi_fname)
bvals, bvecs = read_bvals_bvecs(dwi_bval_fname, dwi_bvec_fname)
This data has 193 volumes. For this demo purpose, we decide to reduce the number of volumes to 5. However, we do not recommended to perform a motion correction with less than 10 volumes.
data_small = data[..., :3]
bvals_small = bvals[:3]
bvecs_small = bvecs[:3]
gtab = gradient_table(bvals_small, bvecs_small)
Start motion correction of our reduced DWI dataset(between-volumes motion correction).
data_corrected, reg_affines = motion_correction(data_small, gtab, affine)
Optimizing level 2 [max iter: 10000]
Optimizing level 1 [max iter: 1000]
Optimizing level 0 [max iter: 100]
Optimizing level 2 [max iter: 10000]
Optimizing level 1 [max iter: 1000]
Optimizing level 0 [max iter: 100]
Optimizing level 2 [max iter: 10000]
Optimizing level 1 [max iter: 1000]
Optimizing level 0 [max iter: 100]
Optimizing level 2 [max iter: 10000]
Optimizing level 1 [max iter: 1000]
Optimizing level 0 [max iter: 100]
Optimizing level 2 [max iter: 10000]
Optimizing level 1 [max iter: 1000]
Optimizing level 0 [max iter: 100]
Optimizing level 2 [max iter: 10000]
Optimizing level 1 [max iter: 1000]
Optimizing level 0 [max iter: 100]
Save our DWI dataset corrected to a new Nifti file.
save_nifti('motion_correction.nii.gz', data_corrected.get_fdata(),
data_corrected.affine)
Jenkinson, M., Smith, S., 2001. A global optimisation method for robust affine registration of brain images. Med Image Anal 5 (2), 143–56.
Total running time of the script: ( 1 minutes 37.137 seconds)